Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455924 | 0.87 | HDAC2 (0.41) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31455697 | 0.85 | ALDH1A1 (0.44) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31455801 | 0.82 | NPC1 (0.46) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31455412 | 0.79 | GSK3B (0.43) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25386272 | 0.79 | MAPT (0.45) | MAPTNPC1RAB9APOLBKDM4E | |
| SCHEMBL31454989 | 0.79 | ABCG2 (0.54) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25384573 | 0.79 | ABCG2 (0.54) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL31420343 | 0.78 | PRMT1 (0.41) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31455719 | 0.77 | ABCG2 (0.45) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL27226131 | 0.71 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |