Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27226100 | 0.88 | KMT2A (0.50) | NPC1RAB9AATMMAPTMAPK1 | |
| SCHEMBL31455550 | 0.82 | MAPT (0.47) | NPC1RAB9AMAPTMAPK1POLB | |
| SCHEMBL31455292 | 0.82 | PRMT1 (0.41) | NPC1RAB9APTPN1PTPN6PTPN11 | |
| SCHEMBL31455818 | 0.82 | PRMT1 (0.41) | NPC1RAB9APTPN1PTPN6PTPN11 | |
| SCHEMBL27226936 | 0.81 | MAPT (0.49) | NPC1RAB9AMAPTMAPK1POLB | |
| SCHEMBL31455494 | 0.81 | HDAC1 (0.44) | NPC1RAB9APTPN1MAPTKMT2A | |
| SCHEMBL27226131 | 0.80 | MAPT (0.60) | NPC1RAB9AMAPTMAPK1POLB | |
| SCHEMBL25384573 | 0.78 | ABCG2 (0.54) | NPC1RAB9AMAPTMAPK1POLB | |
| SCHEMBL31454989 | 0.78 | ABCG2 (0.54) | NPC1RAB9AMAPTMAPK1POLB | |
| SCHEMBL27227362 | 0.77 | MEN1 (0.47) | NPC1RAB9AMAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |