Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903479 | 1.00 | NOTUM (0.57) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL24214174 | 0.88 | NOTUM (0.61) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL17978937 | 0.86 | NOTUM (0.59) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL16094381 | 0.81 | SMN1; SMN2 (0.45) | KDM4EL3MBTL1P4HBCA12CA1 | |
| SCHEMBL1997248 | 0.80 | NOTUM (0.73) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL4129101 | 0.80 | CA1 (0.47) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL10907300 | 0.79 | NOTUM (0.66) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL10861732 | 0.78 | NOTUM (0.64) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL321308 | 0.78 | NOTUM (0.79) | NOTUMKDM4EALDH1A1HTTLMNA | |
| SCHEMBL879847 | 0.78 | ALDH1A1 (0.49) | NOTUMKDM4EALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |