Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455034 | 0.86 | ALDH1A1 (0.39) | HRH4HRH3SKP2MEN1KMT2A | |
| SCHEMBL31454995 | 0.86 | TAS2R14 (0.39) | HRH4HRH3TAS2R14MEN1KMT2A | |
| SCHEMBL31455403 | 0.86 | TAS2R14 (0.39) | HRH4HRH3TAS2R14MEN1KMT2A | |
| SCHEMBL29173102 | 0.78 | MEN1 (0.51) | HRH4HRH3TAS2R14MEN1KMT2A | |
| SCHEMBL29173109 | 0.74 | TAS2R14 (0.38) | HRH4HRH3TAS2R14MEN1KMT2A | |
| SCHEMBL31455549 | 0.73 | ALDH1A1 (0.36) | HRH4HRH3MEN1KMT2AGNRHR | |
| SCHEMBL31455336 | 0.73 | ALDH1A1 (0.36) | HRH4HRH3MEN1KMT2AGNRHR | |
| SCHEMBL4517897 | 0.73 | HRH3 (0.47) | HRH4HRH3MEN1KMT2ALMNA | |
| SCHEMBL31455232 | 0.72 | TAS2R14 (0.41) | TAS2R14GRIN2B | |
| SCHEMBL14938637 | 0.69 | SKP2 (0.53) | HRH3SKP2LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |