Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374309 | 0.75 | PBK (0.39) | LMNAADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL30751356 | 0.73 | PBK (0.40) | LMNAADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL4753462 | 0.67 | CYP2D6 (0.40) | LMNAADORA3ADORA2BADORA2APDE4A | |
| SCHEMBL11480013 | 0.66 | PARP1 (0.39) | ADORA2BADORA2ASMN1; SMN2PARP1 | |
| SCHEMBL25427079 | 0.65 | KDM4E (0.38) | LMNACYP3A4 | |
| SCHEMBL27343202 | 0.65 | NPSR1 (0.36) | LMNACYP1A2CYP3A4 | |
| SCHEMBL1581014 | 0.63 | PDE4A (0.66) | ADORA1ADORA3PDE4APDE4BPDE4C | |
| SCHEMBL1554161 | 0.63 | PDE4A (0.58) | ADORA1ADORA3PDE4APDE4BPDE4C | |
| SCHEMBL30751343 | 0.63 | ADORA1 (0.42) | LMNAADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL27374320 | 0.63 | ADORA1 (0.42) | LMNAADORA1ADORA3ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | claimed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |