Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | PBK | Q96KB5 | 4/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751356 | 0.87 | PBK (0.40) | ADORA1ADORA3ADORA2AADORA2BPBK | |
| SCHEMBL30751428 | 0.81 | PBK (0.34) | PBK | |
| SCHEMBL6467180 | 0.78 | ADORA1 (0.44) | ADORA1ADORA3ADORA2AADORA2BPBK | |
| SCHEMBL21174489 | 0.76 | KDM5B (0.47) | ADORA1ADORA3ADORA2AADORA2BPBK | |
| SCHEMBL31456975 | 0.75 | GRIN2B (0.50) | CYP3A4SMN1; SMN2 | |
| SCHEMBL21174272 | 0.74 | NPC1 (0.44) | LMNACYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL18757752 | 0.73 | AKT2 (0.40) | ADORA1ADORA3ADORA2AKMO | |
| SCHEMBL31456923 | 0.73 | ALDH1A1 (0.46) | ADORA1ADORA2AADORA2BLMNASMN1; SMN2 | |
| SCHEMBL19865524 | 0.72 | EGLN1 (0.35) | ADORA1ADORA2ACYP1A2MAPK1 | |
| SCHEMBL30751370 | 0.72 | CALCA (0.40) | ADORA1ADORA2AADORA2BPBKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |