Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 12/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.47 |
| ▸ | JAK1 | P23458 | 3/20 | 0.47 |
| ▸ | TYK2 | P29597 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.46 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376333 | 1.00 | GRIN2B (0.51) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL31456975 | 0.89 | GRIN2B (0.50) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL31456954 | 0.87 | GRIN2B (0.48) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL31456970 | 0.86 | GRIN2B (0.49) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL30751401 | 0.83 | AADAT (0.44) | GRIN2B | |
| SCHEMBL30751297 | 0.83 | AADAT (0.44) | GRIN2B | |
| SCHEMBL2307512 | 0.77 | GRIN2B (0.72) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL12210756 | 0.75 | SMN1; SMN2 (0.58) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL25291831 | 0.74 | SMN1; SMN2 (0.57) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL9977252 | 0.73 | SMN1; SMN2 (0.54) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |