Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 12/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | JAK1 | P23458 | 3/20 | 0.46 |
| ▸ | TYK2 | P29597 | 3/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456970 | 0.91 | GRIN2B (0.49) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL27376333 | 0.89 | GRIN2B (0.51) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL31456935 | 0.89 | GRIN2B (0.51) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL31456954 | 0.86 | GRIN2B (0.48) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL31457044 | 0.83 | AADAT (0.44) | GRIN2B | |
| SCHEMBL31456986 | 0.83 | AADAT (0.44) | GRIN2B | |
| SCHEMBL27376355 | 0.77 | GRIN2B (0.41) | GRIN2B | |
| SCHEMBL2307512 | 0.77 | GRIN2B (0.72) | GRIN2BSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL30751285 | 0.75 | AADAT (0.43) | GRIN2BMEN1KMT2ANPSR1 | |
| SCHEMBL30751267 | 0.75 | AADAT (0.43) | GRIN2BMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |