Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377968 | 1.00 | JAK2 (0.40) | JAK2JAK1METKITACHE | |
| SCHEMBL27377918 | 0.99 | JAK2 (0.41) | JAK2JAK1METKITACHE | |
| SCHEMBL31456943 | 0.99 | JAK2 (0.41) | JAK2JAK1METKITACHE | |
| SCHEMBL30751335 | 0.87 | MKNK1 (0.41) | JAK2JAK1METGRM2FGFR3 | |
| SCHEMBL27377996 | 0.87 | MKNK1 (0.41) | JAK2JAK1METGRM2FGFR3 | |
| SCHEMBL31457042 | 0.78 | MET (0.46) | JAK2JAK1METGRM2IRAK1 | |
| SCHEMBL30751323 | 0.78 | MET (0.46) | JAK2JAK1METGRM2IRAK1 | |
| SCHEMBL30751290 | 0.78 | GRM2 (0.44) | JAK2METGRM2DYRK1A | |
| SCHEMBL27375154 | 0.78 | GRM2 (0.44) | JAK2METGRM2DYRK1A | |
| SCHEMBL30751300 | 0.77 | MET (0.38) | JAK2JAK1METGRM2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |