Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751323 | 1.00 | MET (0.46) | METDYRK1AGSK3BRIPK2SMN1; SMN2 | |
| SCHEMBL30751290 | 0.88 | GRM2 (0.44) | METDYRK1ASMN1; SMN2PRMT5CA1 | |
| SCHEMBL27375154 | 0.88 | GRM2 (0.44) | METDYRK1ASMN1; SMN2PRMT5CA1 | |
| SCHEMBL30751300 | 0.87 | MET (0.38) | METDYRK1AGSK3BRIPK2CA1 | |
| SCHEMBL27375308 | 0.87 | MET (0.38) | METDYRK1AGSK3BRIPK2CA1 | |
| SCHEMBL31456987 | 0.86 | GRM2 (0.38) | METDYRK1AGSK3BCA1CA2 | |
| SCHEMBL31456992 | 0.86 | MET (0.37) | METDYRK1AGSK3BPRMT5WDR77 | |
| SCHEMBL31456973 | 0.86 | ADRB2 (0.44) | METGRM2TAS2R8 | |
| SCHEMBL30751451 | 0.86 | ADRB2 (0.44) | METGRM2TAS2R8 | |
| SCHEMBL30751302 | 0.86 | MET (0.37) | METDYRK1AGSK3BPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |