Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3149594 | 0.85 | HTR1A (0.37) | HTR1ADRD2SLC2A1KCNH2CDK4 | |
| Hydrochloric Acid SCHEMBL3145852 | 0.84 | HTR1A (0.37) | HTR1ADRD2SLC2A1KCNH2CDK4 | |
| SCHEMBL3141765 | 0.79 | SLC2A1 (0.42) | SLC2A1KCNH2 | |
| SCHEMBL3641658 | 0.79 | HTR1A (0.35) | HTR1ADRD2 | |
| SCHEMBL3394012 | 0.79 | SLC2A1 (0.46) | HTR1ADRD2SLC2A1KCNH2 | |
| SCHEMBL3676325 | 0.79 | SLC2A1 (0.36) | HTR1ADRD2SLC2A1KCNH2 | |
| SCHEMBL2291274 | 0.78 | HTR1A (0.43) | HTR1ADRD2KCNH2CDK4CCND1 | |
| SCHEMBL3209025 | 0.78 | SLC2A1 (0.40) | HTR1ADRD2SLC2A1KCNH2 | |
| SCHEMBL2287760 | 0.73 | HTR1A (0.40) | HTR1ADRD2CDK4CCND1 | |
| SCHEMBL3141859 | 0.72 | KCNH2 (0.69) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136807-B1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LTD (GB) | 2010-11-03 | — | — | EP | disclosed |
| EP-1954697-B1 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2010-02-24 | — | — | EP | disclosed |