Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457044 | 1.00 | AADAT (0.44) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL30751267 | 0.91 | AADAT (0.43) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL30751285 | 0.91 | AADAT (0.43) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL30751297 | 0.90 | AADAT (0.44) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL30751401 | 0.90 | AADAT (0.44) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL30751369 | 0.86 | AADAT (0.42) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL30751365 | 0.86 | AADAT (0.42) | AADATGRIN2BPREPTMEM97SIGMAR1 | |
| SCHEMBL31457053 | 0.84 | GRIN2B (0.41) | AADATGRIN2BTMEM97SIGMAR1LMNA | |
| SCHEMBL30751273 | 0.84 | GRIN2B (0.41) | AADATGRIN2BTMEM97SIGMAR1LMNA | |
| SCHEMBL31456975 | 0.83 | GRIN2B (0.50) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |