SCHEMBL31457403

SCHEMBL31457403

CCS(=O)(=O)CCCN1CCN(C)CC1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.44
SIGMAR1 Q99720 1/20 0.38
HTR7 P34969 1/20 0.38
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36
USP2 O75604 2/20 0.36
GNAI3 P08754 2/20 0.35
GNAO1 P09471 2/20 0.35
GNAI1 P63096 2/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4564530 0.91 PAOX (0.47) PAOXSIGMAR1HTR7CSNK2A2CSNK2B
SCHEMBL18803169 0.87 PAOX (0.38) PAOXSIGMAR1HTR7USP2SMN1; SMN2
SCHEMBL31457399 0.82 MEN1 (0.35) PAOXUSP2SMN1; SMN2ALDH1A1HPGD
SCHEMBL22014790 0.82 PAOX (0.41) PAOXSIGMAR1HTR7CSNK2A2CSNK2B
SCHEMBL4369887 0.80 CXCR4 (0.46) SIGMAR1GNAI3GNAO1GNAI1SMN1; SMN2
SCHEMBL18463182 0.80 KEAP1 (0.48) PAOXSIGMAR1USP2SMN1; SMN2ALDH1A1
SCHEMBL3903911 0.79 PAOX (0.44) PAOXSIGMAR1HTR7CSNK2A2CSNK2B
SCHEMBL3903913 0.79 PAOX (0.44) PAOXSIGMAR1HTR7CSNK2A2CSNK2B
SCHEMBL4352917 0.79 PAOX (0.48) PAOXSIGMAR1HTR7CSNK2A2CSNK2B
Hydrochloric Acid SCHEMBL1546950 0.79 CXCR4 (0.44) SIGMAR1GNAI3GNAO1GNAI1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371407-A 2, 5-Diketopiperazine compound with anti-tumor effect and application thereof in preparing medicament for treating and/or preventing neutropenia 青岛海合生物科技有限公司 2025-01-28 CN disclosed