Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601219 | 0.86 | ADORA3 (0.51) | ADORA3ADORA2AADORA1KDM4EL3MBTL1 | |
| SCHEMBL29615773 | 0.85 | ADORA3 (0.50) | ADORA3ADORA2AADORA1KDM4EKLK6 | |
| SCHEMBL23292948 | 0.78 | AURKA (0.34) | ADORA3ADORA2AADORA1KDM4EJAK2 | |
| SCHEMBL29600778 | 0.75 | KDM4E (0.50) | ADORA3ADORA2AADORA1KDM4EL3MBTL1 | |
| SCHEMBL18746475 | 0.74 | KDM4E (0.45) | KDM4EL3MBTL1MAP2K1MAPTALDH1A1 | |
| SCHEMBL30997961 | 0.72 | ADORA3 (0.45) | ADORA3ADORA2AADORA1KDM4ESTAT3 | |
| SCHEMBL30976395 | 0.71 | KDM4E (0.51) | KDM4EL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL30800015 | 0.70 | KDM4E (0.44) | ADORA3ADORA2AADORA1KDM4EL3MBTL1 | |
| SCHEMBL16517165 | 0.70 | KDM4E (0.60) | KDM4EL3MBTL1STAT3HIF1AMAP2K1 | |
| SCHEMBL19249486 | 0.68 | KDM4E (0.43) | KDM4EL3MBTL1KCNMA1PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109061-B | Tricyclic compounds | 北京加科思新药研发有限公司 | 2025-01-28 | — | — | CN | disclosed |