Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604440 | 0.98 | APP (0.33) | APPMAPTPDK2CHRM5 | |
| SCHEMBL24620697 | 0.97 | APP (0.33) | APPMAPTPDK2 | |
| SCHEMBL19547563 | 0.94 | MAPT (0.30) | MAPT | |
| SCHEMBL3147166 | 0.94 | NPC1 (0.33) | APPMAPTPDK2CHRM5 | |
| SCHEMBL25604183 | 0.93 | PDK2 (0.33) | APPMAPTPDK2CHRM5 | |
| SCHEMBL4040445 | 0.93 | PGR (0.33) | APPMAPTPDK2CHRM5 | |
| SCHEMBL3155860 | 0.93 | ALDH1A1 (0.33) | MAPTPDK2 | |
| SCHEMBL25604193 | 0.93 | PDK2 (0.31) | PDK2 | |
| SCHEMBL14617523 | 0.92 | PGR (0.34) | MAPT | |
| SCHEMBL25604441 | 0.92 | PDK2 (0.35) | MAPTPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331581-B1 | MECHANOPHORIC MEDICAL PRODUKT | AESCULAP AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-1966180-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-1963896-B1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL INC (US) | 2010-02-10 | — | — | EP | disclosed |