Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459970 | 0.84 | ALDH1A1 (0.42) | TSHRKDM4ELMNAL3MBTL1MEN1 | |
| SCHEMBL31459931 | 0.81 | CYP4F2 (0.41) | TSHRKDM4ELMNAL3MBTL1GAA | |
| SCHEMBL31460329 | 0.80 | BAZ2B (0.35) | KDM4ELMNAGAAKMT2ACA12 | |
| SCHEMBL31459871 | 0.79 | BAZ2B (0.39) | TSHRKDM4ELMNAL3MBTL1GAA | |
| SCHEMBL12491190 | 0.76 | TSHR (0.47) | TSHRKDM4EGAAMEN1KMT2A | |
| SCHEMBL6853629 | 0.75 | GAA (0.39) | TSHRKDM4ELMNAL3MBTL1GAA | |
| SCHEMBL13214896 | 0.73 | — | — | |
| SCHEMBL5906668 | 0.73 | TSHR (0.43) | JUNNFKB1NFKB2RELATSHR | |
| SCHEMBL14901138 | 0.72 | CYP2C9 (0.43) | TSHRLMNAL3MBTL1GAAKMT2A | |
| SCHEMBL22979644 | 0.69 | TSHR (0.40) | TSHRKDM4ELMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |