Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459997 | 0.75 | JUN (0.38) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9461194 | 0.73 | JMJD6 (0.44) | KMT2AMAPTALDH1A1NPC1HTT | |
| SCHEMBL29111665 | 0.72 | KMT2A (0.41) | KMT2AMAPTALDH1A1NPC1HTT | |
| SCHEMBL22040159 | 0.72 | JMJD6 (0.45) | KMT2AMAPTALDH1A1NPC1HTT | |
| SCHEMBL9734881 | 0.71 | NOTUM (0.45) | GAAKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL14901138 | 0.71 | CYP2C9 (0.43) | GAAKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL6855286 | 0.71 | KMT2A (0.40) | KMT2AKDM4EMAPTALDH1A1HTT | |
| SCHEMBL22040162 | 0.70 | ADORA1 (0.45) | KMT2AKDM4EMAPTNPC1SMN1; SMN2 | |
| SCHEMBL31459970 | 0.69 | ALDH1A1 (0.42) | KMT2AKDM4EALDH1A1NPC1NPSR1 | |
| SCHEMBL4670651 | 0.69 | KMT2A (0.39) | KMT2AMAPTALDH1A1HTTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |