Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707074 | 0.89 | KRAS (0.34) | KRAS | |
| SCHEMBL30706707 | 0.85 | CCNC (0.32) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL30706928 | 0.79 | KRAS (0.46) | KRAS | |
| SCHEMBL30707008 | 0.77 | KRAS (0.51) | KRAS | |
| SCHEMBL31460204 | 0.74 | KRAS (0.44) | KRAS | |
| SCHEMBL34461950 | 0.74 | FFAR2 (0.41) | KDM4EALDH1A1LMNANPSR1MAPT | |
| SCHEMBL24536169 | 0.73 | KRAS (0.33) | KRAS | |
| SCHEMBL24536186 | 0.73 | KRAS (0.33) | KRAS | |
| SCHEMBL30707499 | 0.72 | KRAS (0.56) | KRAS | |
| SCHEMBL30600136 | 0.70 | MAPT (0.48) | KDM4EALDH1A1LMNANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |