Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486360 | 0.83 | PDK2 (0.36) | PDK2BRD4POLBL3MBTL1CHRM2 | |
| SCHEMBL6195464 | 0.82 | PTGER4 (0.37) | PDK2BRD4POLB | |
| SCHEMBL6195462 | 0.82 | PTGER4 (0.37) | PDK2BRD4POLB | |
| SCHEMBL12301049 | 0.80 | L3MBTL1 (0.39) | BRD4L3MBTL1 | |
| SCHEMBL11929360 | 0.80 | L3MBTL1 (0.39) | BRD4L3MBTL1 | |
| SCHEMBL1712652 | 0.80 | PDK2 (0.39) | PDK2BRD4POLBL3MBTL1CHRM2 | |
| SCHEMBL11949258 | 0.80 | L3MBTL1 (0.39) | BRD4L3MBTL1 | |
| SCHEMBL1712920 | 0.78 | PDK2 (0.39) | PDK2BRD4POLB | |
| SCHEMBL1712647 | 0.77 | PDK2 (0.41) | PDK2BRD4POLBL3MBTL1 | |
| SCHEMBL11563570 | 0.77 | PDK2 (0.33) | PDK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |