Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.31 |
| ▸ | PER2 | O15055 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949258 | 0.83 | L3MBTL1 (0.39) | BRD4L3MBTL1 | |
| SCHEMBL12301049 | 0.83 | L3MBTL1 (0.39) | BRD4L3MBTL1 | |
| SCHEMBL11929360 | 0.83 | L3MBTL1 (0.39) | BRD4L3MBTL1 | |
| SCHEMBL1712652 | 0.83 | PDK2 (0.39) | PDK2BRD4L3MBTL1POLBCHRM2 | |
| SCHEMBL31460081 | 0.83 | PDK2 (0.34) | PDK2BRD4L3MBTL1POLBCHRM2 | |
| SCHEMBL1712920 | 0.82 | PDK2 (0.39) | PDK2BRD4POLBPTGER4PTGER3 | |
| SCHEMBL11563570 | 0.80 | PDK2 (0.33) | PDK2BRD4PER2 | |
| SCHEMBL1712647 | 0.80 | PDK2 (0.41) | PDK2BRD4L3MBTL1POLBPTGER4 | |
| SCHEMBL9851985 | 0.79 | CYP3A4 (0.33) | PDK2BRD4 | |
| SCHEMBL9851987 | 0.79 | CYP3A4 (0.33) | PDK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014191-A1 | PYRROLIDIN-2-ONE COMPOUNDS AND THEIR USE AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1999-03-25 | — | — | WO | claimed |
| WO-1999014191-A1 | PYRROLIDIN-2-ONE COMPOUNDS AND THEIR USE AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1999-03-25 | — | — | WO | disclosed |