SCHEMBL31460397

SCHEMBL31460397

Cc1c([Si](C)(C)C)n(-c2ccccc2[Si](C)(C)C)c2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
TSHR P16473 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP11B2 P19099 1/20 0.31
GSR P00390 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GPR3 P46089 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31460407 0.71 KDM4E (0.36) ALDH1A1KDM4EL3MBTL1TSHRGLA
SCHEMBL28444000 0.67 ALDH1A1 (0.36) ALDH1A1KDM4EATML3MBTL1RAB9A
SCHEMBL31609567 0.67 ALDH1A1 (0.38) ALDH1A1KDM4EATML3MBTL1HPGD
SCHEMBL24775106 0.67 ALDH1A1 (0.38) ALDH1A1KDM4EATML3MBTL1GSR
SCHEMBL16431969 0.67 ALDH1A1 (0.38) ALDH1A1KDM4EATML3MBTL1HPGD
SCHEMBL10029971 0.65 ALDH1A1 (0.50) ALDH1A1KDM4EATML3MBTL1TSHR
SCHEMBL31460266 0.65 TNFRSF1A (0.38) ALDH1A1KDM4ETSHRHPGDHTT
SCHEMBL10029990 0.65 ALDH1A1 (0.46) ALDH1A1KDM4EATML3MBTL1TSHR
SCHEMBL21446133 0.63 TSHR (0.47) ALDH1A1KDM4EATML3MBTL1TSHR
SCHEMBL16448299 0.62 ALDH1A1 (0.47) ALDH1A1KDM4EATML3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371451-A Method for efficiently synthesizing silicon-based indole compound 南阳师范学院 2025-01-28 CN disclosed