SCHEMBL16448299

SCHEMBL16448299

c1ccc([Si](c2ccccc2)(c2ccccc2-n2c3ccccc3c3ccccc32)c2ccccc2-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
KDM4E B2RXH2 2/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GPR3 P46089 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
CYP19A1 P11511 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.32
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
SLC6A2 P23975 1/20 0.30
FABP3 P05413 1/20 0.30
FABP4 P15090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24064820 0.85 KDM4E (0.43) ALDH1A1KDM4EATML3MBTL1
SCHEMBL17463244 0.82 KDM4E (0.49) ALDH1A1KDM4EATML3MBTL1TSHR
SCHEMBL18089899 0.81 ALDH1A1 (0.39) ALDH1A1KDM4EATML3MBTL1
SCHEMBL18089888 0.81 ALDH1A1 (0.39) ALDH1A1KDM4EATML3MBTL1CYP19A1
SCHEMBL22432385 0.80 ALDH1A1 (0.41) ALDH1A1KDM4EATML3MBTL1DUSP3
SCHEMBL12795606 0.80 KDM4E (0.40) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL31643612 0.77 L3MBTL1 (0.38) ALDH1A1KDM4EATML3MBTL1CYP1A2
SCHEMBL21687830 0.76 ALDH1A1 (0.35) ALDH1A1KDM4EATML3MBTL1TSHR
SCHEMBL21687781 0.75 SMN1; SMN2 (0.37) ALDH1A1KDM4EATML3MBTL1CYP1A2
SCHEMBL21687635 0.75 SMN1; SMN2 (0.37) ALDH1A1KDM4EATML3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2999766-A1 PRODUCTION OF ORGANIC PHOSPHORESCENT LAYERS WITH ADDITION OF HEAVY MAIN GROUP METAL COMPLEXES Siemens Aktiengesellschaft (DE) 2016-03-30 EP disclosed
WO-2015018539-A1 PRODUCTION OF ORGANIC PHOSPHORESCENT LAYERS WITH ADDITION OF HEAVY MAIN GROUP METAL COMPLEXES SIEMENS AKTIENGESELLSCHAFT (DE) 2015-02-12 WO disclosed