Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459871 | 0.88 | BAZ2B (0.39) | GAASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL31460256 | 0.87 | METAP2 (0.33) | SMN1; SMN2LMNATSHRALDH1A1NPC1 | |
| SCHEMBL31460203 | 0.81 | CYP2C19 (0.32) | TSHR | |
| SCHEMBL31459931 | 0.79 | CYP4F2 (0.41) | GAALMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL30706873 | 0.76 | GAA (0.35) | GAASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL31460329 | 0.72 | BAZ2B (0.35) | GAASMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL30706926 | 0.67 | ALDH1A1 (0.41) | GAASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL31459970 | 0.67 | ALDH1A1 (0.42) | SMN1; SMN2LMNATSHRALDH1A1L3MBTL1 | |
| SCHEMBL24536525 | 0.65 | ALDH1A1 (0.37) | GAASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL30706947 | 0.64 | NR4A3 (0.36) | GAASMN1; SMN2LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |