Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461730 | 0.78 | RAB9A (0.36) | ALDH1A1L3MBTL1SMN1; SMN2PDE4BHPGD | |
| SCHEMBL31461656 | 0.76 | MAOB (0.35) | ALDH1A1L3MBTL1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL31461692 | 0.73 | MAOB (0.32) | ALDH1A1SMN1; SMN2PDE4BHPGDMEN1 | |
| SCHEMBL31461713 | 0.71 | TDP1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2KMT2APOLB | |
| SCHEMBL31461660 | 0.70 | HPGD (0.43) | ALDH1A1SMN1; SMN2HTTHPGDMEN1 | |
| SCHEMBL31461683 | 0.68 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTHPGDKDM4EMAPT | |
| SCHEMBL31461684 | 0.68 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTHPGDKDM4EMAPT | |
| SCHEMBL23645175 | 0.66 | EGFR (0.45) | EGFRBTKNPC1RAB9A | |
| SCHEMBL23623281 | 0.65 | EGFR (0.43) | EGFRBTKNPC1RAB9A | |
| SCHEMBL31571970 | 0.65 | EGFR (0.52) | EGFRBTKHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |