Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461657 | 0.92 | HDAC3 (0.39) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23611718 | 0.89 | SMN1; SMN2 (0.43) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29930729 | 0.88 | ALOX15 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL23611755 | 0.88 | ALOX15 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL23623437 | 0.86 | HPGD (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL23611751 | 0.86 | SMN1; SMN2 (0.41) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31461708 | 0.86 | OPRM1 (0.41) | ALDH1A1KDM4EHPGDRCE1 | |
| SCHEMBL31461684 | 0.85 | SMN1; SMN2 (0.42) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31461683 | 0.85 | SMN1; SMN2 (0.42) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23623626 | 0.83 | SMN1; SMN2 (0.40) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |