Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.39 |
| ▸ | HCN1 | O60741 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623349 | 0.90 | HSD17B13 (0.41) | RORCLMNAHTTSLC6A9OPRM1 | |
| SCHEMBL26601319 | 0.88 | OPRM1 (0.41) | EGFRBTKRORCOPRM1KDM4E | |
| SCHEMBL23623576 | 0.87 | KCNK3 (0.43) | LMNAHTTSLC6A9EPHX2KDM4E | |
| SCHEMBL23623344 | 0.85 | OPRM1 (0.42) | RORCOPRM1EPHX2HSD17B13HCN1 | |
| SCHEMBL26601342 | 0.85 | AKR1B1 (0.46) | RORCLMNAHTTOPRM1HCN1 | |
| SCHEMBL23623811 | 0.84 | KCNK3 (0.50) | LMNAKDM4EALDH1A1HCN1KCNK3 | |
| SCHEMBL31461705 | 0.83 | RXFP1 (0.42) | RORCOPRM1KDM4EALDH1A1HSD17B13 | |
| SCHEMBL23623292 | 0.83 | KCNK3 (0.41) | RORCOPRM1EPHX2HSD17B13HCN1 | |
| SCHEMBL23623486 | 0.82 | HCN1 (0.41) | RORCOPRM1HSD17B13HCN1KCNK3 | |
| SCHEMBL23623810 | 0.82 | HCN1 (0.41) | RORCOPRM1EPHX2HSD17B13HCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |