SCHEMBL31461682

SCHEMBL31461682

NC(=O)c1cnc2c(c1)CN=C2

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NNMT P40261 8/20 0.47
SMN1; SMN2 Q16637 1/20 0.38
PSMD14 O00487 1/20 0.36
STAMBP O95630 1/20 0.36
COPS5 Q92905 1/20 0.36
HPGDS O60760 2/20 0.35
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP11B2 P19099 1/20 0.32
MKNK1 Q9BUB5 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31
AKT1 P31749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28106132 0.98 NNMT (0.46) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL30255493 0.79 NNMT (0.47) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL35211576 0.73 NNMT (0.45) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL17675123 0.70 NNMT (0.49) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL16495711 0.69 NNMT (0.56) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL30370430 0.69 NNMT (0.48) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL26607684 0.67 NNMT (0.58) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL17675163 0.67 NNMT (0.58) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL6282473 0.66 NNMT (0.51) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL31239059 0.66 NNMT (0.51) NNMTSMN1; SMN2PSMD14STAMBPCOPS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025097247-A1 METHOD OF TREATMENT OF FIBROSIS WITH INVERSE AGONIST OF RAR RELATED ORPHAN RECEPTORS (RORS) 11949098 CANADA INC. (CA) 2025-05-15 WO claimed
WO-2025097247-A1 METHOD OF TREATMENT OF FIBROSIS WITH INVERSE AGONIST OF RAR RELATED ORPHAN RECEPTORS (RORS) 11949098 CANADA INC. (CA) 2025-05-15 WO disclosed