Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | EIF4E | P06730 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461684 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EALPLMAPTHTT | |
| SCHEMBL31461683 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EALPLMAPTHTT | |
| SCHEMBL31461657 | 0.86 | HDAC3 (0.39) | SMN1; SMN2KDM4EMAPTALDH1A1HTT | |
| SCHEMBL23611738 | 0.86 | ALOX15 (0.44) | ALPLMAPTALDH1A1MAPK1NTRK1 | |
| SCHEMBL23611767 | 0.82 | TP53 (0.42) | SMN1; SMN2MAPTNTRK1HPGDLMNA | |
| SCHEMBL23623267 | 0.81 | TP53 (0.42) | SMN1; SMN2MAPTALDH1A1HTTMAPK1 | |
| SCHEMBL23623626 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTALDH1A1HTTMAPK1 | |
| SCHEMBL31461685 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4EALPLMAPTHTT | |
| SCHEMBL23611718 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALPLMAPTALDH1A1 | |
| SCHEMBL23611755 | 0.77 | ALOX15 (0.47) | SMN1; SMN2ALPLMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |