Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | HCN1 | O60741 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461683 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EALPLHTTHPGD | |
| SCHEMBL31461684 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EALPLHTTHPGD | |
| SCHEMBL23623280 | 0.85 | ALOX15 (0.47) | ALPLGAAADORA2AADORA1HPGD | |
| SCHEMBL31461708 | 0.85 | OPRM1 (0.41) | KDM4EADORA2AADORA1HPGDOPRM1 | |
| SCHEMBL23623443 | 0.83 | HPGD (0.45) | KDM4EADORA2AADORA1HPGDOPRM1 | |
| SCHEMBL31461680 | 0.81 | ALOX15 (0.42) | KDM4EADORA2AADORA1OPRM1HCN1 | |
| SCHEMBL23623256 | 0.80 | OPRM1 (0.39) | ADORA2AADORA1OPRM1HCN1MAPT | |
| SCHEMBL31461698 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EALPLHTTHPGD | |
| SCHEMBL23611716 | 0.79 | KCNK3 (0.45) | SMN1; SMN2ADORA2AADORA1HTTHPGD | |
| SCHEMBL29930594 | 0.79 | KCNK3 (0.45) | SMN1; SMN2ADORA2AADORA1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |