Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921417 | 0.83 | ALDH1A1 (0.41) | RIPK1ALDH1A1RAB9AKMT2ACHRNB2 | |
| SCHEMBL31462365 | 0.81 | GRIA4 (0.35) | RIPK1GRIA4ALDH1A1RAB9AKMT2A | |
| SCHEMBL31462369 | 0.80 | ALDH1A1 (0.40) | RIPK1ALDH1A1RAB9AKMT2ACHRNB2 | |
| SCHEMBL31462373 | 0.78 | ALDH1A1 (0.54) | ALDH1A1RAB9AKMT2A | |
| SCHEMBL31462379 | 0.77 | RIPK1 (0.40) | RIPK1ALDH1A1RAB9AKMT2A | |
| SCHEMBL31462375 | 0.76 | ALDH1A1 (0.37) | RIPK1ALDH1A1RAB9AKMT2ACHRNB2 | |
| SCHEMBL31462364 | 0.75 | TSHR (0.43) | RIPK1ALDH1A1KMT2A | |
| SCHEMBL31462383 | 0.74 | NPC1 (0.37) | RIPK1ALDH1A1RAB9AKMT2A | |
| SCHEMBL31462368 | 0.73 | RIPK1 (0.43) | RIPK1ALDH1A1RAB9AKMT2ACHRNB2 | |
| SCHEMBL31462374 | 0.72 | ALDH1A1 (0.35) | RIPK1ALDH1A1RAB9AKMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684225-A | Isoxazolidine RIPK1 inhibitor and application thereof | 中国药科大学 | 2025-03-25 | — | — | CN | disclosed |