Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159788 | 0.84 | HCAR3 (0.42) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL31463453 | 0.84 | KMT2A (0.37) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL31463454 | 0.84 | KMT2A (0.37) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL30087168 | 0.83 | MAPT (0.46) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29170113 | 0.83 | MAPT (0.46) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL30087167 | 0.83 | MAPT (0.46) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29170112 | 0.83 | MAPT (0.46) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL30966502 | 0.80 | ALDH1A1 (0.44) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL31160113 | 0.79 | MAPT (0.43) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29170125 | 0.79 | HCAR3 (0.53) | HCAR3KMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021048-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2025-01-30 | — | — | WO | disclosed |