Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 14/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150604 | 0.77 | PIK3CA (0.49) | PIK3C3PRKDCPIK3CAPDE3BPDE3A | |
| SCHEMBL4588676 | 0.77 | MAPT (0.47) | HRH3 | |
| SCHEMBL4588673 | 0.77 | MAPT (0.47) | HRH3 | |
| SCHEMBL22796057 | 0.75 | JAK3 (0.47) | PRKDCHRH3 | |
| SCHEMBL23291829 | 0.74 | FFAR4 (0.41) | ATMPIK3C3PRKDCATRPIK3CA | |
| SCHEMBL23111658 | 0.74 | FFAR4 (0.41) | ATMPIK3C3PRKDCATRPIK3CA | |
| SCHEMBL30403552 | 0.74 | NOTUM (0.50) | — | |
| SCHEMBL26633119 | 0.74 | NOTUM (0.50) | — | |
| SCHEMBL14983939 | 0.72 | PRKDC (0.46) | ATMPIK3C3PRKDCATRPIK3CA | |
| SCHEMBL18860543 | 0.72 | ZAP70 (0.42) | PIK3CANR3C2MTORPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069366-B1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION INC (US) | 2025-03-19 | — | — | EP | disclosed |