Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docusate SCHEMBL2636159 | 0.99 | RECQL (0.66) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL23706351 | 0.99 | RECQL (0.66) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL8468326 | 0.97 | RECQL (0.63) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL8468204 | 0.97 | RECQL (0.63) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL8469170 | 0.97 | RECQL (0.63) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL4252993 | 0.96 | RECQL (0.69) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL19305303 | 0.95 | RECQL (0.67) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL3041223 | 0.93 | RECQL (0.78) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL9722552 | 0.93 | RECQL (0.78) | RECQLCYP3A4TSHRATMTDP1 | |
| Docusate SCHEMBL4113 | 0.93 | RECQL (0.78) | RECQLCYP3A4TSHRATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7641727-B2 | Electrode level difference absorbing print paste and method of producing electronic device | TDK CORPORATION (JP) | 2010-01-05 | — | — | US | claimed |
| US-4992830-A | Image recording apparatus that prevents toner dispersion | KABUSHIKI KAISHA TOSHIBA (JP) | 1991-02-12 | — | — | US | claimed |
| EP-3255074-B1 | PHOTOELASTIC POLYURETHANE RESIN, DETECTION MEMBER, ROBOT, AND METHOD FOR PRODUCING PHOTOELASTIC POLYURETHANE RESIN | MITSUI CHEMICALS INC (JP) | 2024-05-29 | — | — | EP | disclosed |
| EP-3690503-B1 | GLASS STRUCTURE | SEKISUI CHEMICAL CO LTD (JP) | 2024-04-03 | — | — | EP | disclosed |
| CN-114921036-B | High-low temperature resistant polyvinyl chloride alloy elastomer polymer and preparation method thereof | 东莞市明凯塑胶科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-3560900-B1 | SEALING MATERIAL FOR MULTI-LAYERED GLASSES, AND MULTI-LAYERED GLASS | DAINIPPON INK & CHEMICALS (JP) | 2023-08-30 | — | — | EP | disclosed |
| US-11440296-B2 | Laminated glass intermediate film and laminated glass | SEKISUI CHEMICAL CO., LTD. (JP) | 2022-09-13 | — | — | US | disclosed |
| CN-114015116-A | Preparation method of aluminum hydroxide surface modified expandable graphite flame retardant and method for preparing flame-retardant polyurethane foam plastic by using same | 哈尔滨工程大学 | 2022-02-08 | — | — | CN | disclosed |
| US-11048112-B2 | Glass structure | SEKISUI CHEMICAL CO., LTD. (JP) | 2021-06-29 | — | — | US | disclosed |
| US-10982123-B2 | Sealing material for multi-layered glasses, and multi-layered glass | DIC CORPORATION (JP) | 2021-04-20 | — | — | US | disclosed |
| EP-3760600-A1 | LAMINATED GLASS INTERMEDIATE FILM AND LAMINATED GLASS | SEKISUI CHEMICAL CO., LTD. (JP) | 2021-01-06 | — | — | EP | disclosed |
| US-6248497-B1 | LIGHT SENSITIVE AND HEAT SENSITIVE RECORDING IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| CN-1175523-A | Hybrid inflator | OEA INC (US) | 1998-03-11 | — | — | CN | disclosed |
| EP-0528560-B1 | A combination extrusion head assembly for producing weather strip | KINUGAWA RUBBER IND (JP) | 1996-09-11 | — | — | EP | disclosed |
| CN-1114109-A | Colorant composition | ASAHI CHEMICAL IND (JP) | 1995-12-27 | — | — | CN | disclosed |
| US-5267846-A | Device for producing weather strip | KINUGAWA RUBBER IND. CO., LTD. (JP) | 1993-12-07 | — | — | US | disclosed |
| EP-0528560-A1 | A combination extrusion head assembly for producing weather strip | KINUGAWA RUBBER IND. CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-4992830-A | Image recording apparatus that prevents toner dispersion | KABUSHIKI KAISHA TOSHIBA (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-86104468-A | The processing technique of aloe product and relevant application thereof | — | 1986-12-31 | — | — | CN | disclosed |
| US-4388165-A | Selective ion sensitive electrode and method of making it | OLYMPUS OPTICAL COMPANY LTD. (JP) | 1983-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11048112-B2 | Glass structure | RPL12, RPL13A, ATG13 | RECQL 1436/4885CYP3A4 1222/4885TSHR 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.