Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.38 |
| ▸ | PPARG known ✓ | P37231 | 4/20 | 0.36 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.36 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docusate SCHEMBL23706351 | 1.00 | RECQL (0.66) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL3146370 | 0.99 | RECQL (0.67) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL8469170 | 0.98 | RECQL (0.63) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL8468326 | 0.98 | RECQL (0.63) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL8468204 | 0.98 | RECQL (0.63) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL4252993 | 0.95 | RECQL (0.69) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL19305303 | 0.94 | RECQL (0.67) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL11709081 | 0.93 | RECQL (0.69) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL6239044 | 0.92 | RECQL (0.74) | RECQLTSHRTDP1CYP3A4ATM | |
| Docusate SCHEMBL3041223 | 0.92 | RECQL (0.78) | RECQLTSHRTDP1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992830-A | Image recording apparatus that prevents toner dispersion | KABUSHIKI KAISHA TOSHIBA (JP) | 1991-02-12 | — | — | US | claimed |
| JP-62169043-A | — | — | None | — | — | JP | disclosed |
| EP-3255074-B1 | PHOTOELASTIC POLYURETHANE RESIN, DETECTION MEMBER, ROBOT, AND METHOD FOR PRODUCING PHOTOELASTIC POLYURETHANE RESIN | MITSUI CHEMICALS INC (JP) | 2024-05-29 | — | — | EP | disclosed |
| US-20230173099-A1 | LIPOLYSIS COMPOSITION USING SURFACE-MODIFIED GAS-GENERATING NANOPARTICLES | SUPERNOVA BIO CO., LTD. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-11518735-B2 | Pseudoceramide compound with improved stability and composition comprising same | AE KYUNG INDUSTRIAL CO., LTD. (KR) | 2022-12-06 | — | — | US | disclosed |
| EP-4079299-A1 | LIPOLYSIS COMPOSITION USING SURFACE-MODIFIED GAS-GENERATING NANOPARTICLES | Supernova Bio Co., Ltd. (KR) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021006100-A1 | RUBBER COMPOSITION, METHOD FOR PRODUCING SAME, UNVULCANIZED MOLDED ARTICLE, VULCANIZED PRODUCT, AND VULCANIZED MOLDED ARTICLE | デンカ株式会社 | 2021-01-14 | — | — | WO | disclosed |
| US-20200354309-A1 | NOVEL PSEUDOCERAMIDE COMPOUND WITH IMPROVED STABILITY AND COMPOSITION COMPRISING SAME | AE KYUNG INDUSTRIAL CO., LTD (KR) | 2020-11-12 | — | — | US | disclosed |
| US-10695314-B2 | Antimicrobial composition containing 7,10-epoxyoctadeca-7,9-dienoic acid as active ingredient | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2020-06-30 | — | — | US | disclosed |
| US-10626213-B2 | Photoelastic polyurethane resin, detection member, robot, and method for producing photoelastic polyurethane resin | MITSUI CHEMICALS, INC. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20110034357-A1 | COMPOSITION AND METHOD FOR FORMING COATING FILM | FUJIFILM CORPORATION (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2267106-A1 | COMPOSITION AND METHOD FOR FORMING COATING FILM | FUJIFILM Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-6720287-B2 | WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED | FUJI PHOTO FILM CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| US-20030045426-A1 | Heat sensitive recording material and microcapsule solution | FUJI PHOTO FILM CO., LTD. | 2003-03-06 | — | — | US | disclosed |
| EP-0697615-A2 | Display device | FUJIKURA LTD. (JP) | 1996-02-21 | — | — | EP | disclosed |
| US-5213675-A | Lamination films covering surfaces of electroconductive substrates and silver halide films | TERUMO KABUSHIKI KAISHA (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5066383-A | REFERENCE ELECTRODE, ION SENSOR AND METHOD OF MANUFACTURING THE SAME | TERUMO KABUSHIKI KAISHA (JP) | 1991-11-19 | — | — | US | disclosed |
| US-4992830-A | Image recording apparatus that prevents toner dispersion | KABUSHIKI KAISHA TOSHIBA (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0366566-A2 | Reference electrode, ion sensor and method of manufacturing the same | TERUMO KABUSHIKI KAISHA (JP) | 1990-05-02 | — | — | EP | disclosed |
| JP-S62169043-A | PH SENSOR | TERUMO CORP | 1987-07-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518735-B2 | Pseudoceramide compound with improved stability and composition comprising same | CERS2, ASAH2, ASAH1 | CA2 534/4885PPARG 2425/4885PDE4A 667/4885 |
| US-20200354309-A1 | NOVEL PSEUDOCERAMIDE COMPOUND WITH IMPROVED STABILITY AND COMPOSITION COMPRISING SAME | CERS2, ASAH2, CERT1 | CA2 624/4885PPARG 3069/4885PDE4A 735/4885 |
| US-10695314-B2 | Antimicrobial composition containing 7,10-epoxyoctadeca-7,9-dienoic acid as active ingredient | CYP51A1, IL17A, ELOVL5 | CA2 4353/4885PPARG 1494/4885PDE4A 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.