Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060067 | 0.92 | KMT2A (0.56) | KMT2AGAAPOLBNPC1ALDH1A1 | |
| SCHEMBL2900687 | 0.89 | KMT2A (0.65) | KMT2AGAAPOLBALDH1A1KDM4E | |
| SCHEMBL6788470 | 0.83 | KMT2A (0.57) | KMT2AGAAPOLBALDH1A1KDM4E | |
| SCHEMBL6859316 | 0.80 | KMT2A (0.54) | KMT2AGAAPOLBALDH1A1KDM4E | |
| SCHEMBL346578 | 0.80 | TSHR (0.67) | KMT2AGAAPOLBNPC1ALDH1A1 | |
| SCHEMBL5240208 | 0.79 | LCK (0.53) | KMT2AGAAALDH1A1KDM4EHSD17B2 | |
| SCHEMBL1964834 | 0.78 | HTR4 (0.53) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL6584127 | 0.78 | HTR4 (0.53) | KMT2AGAAALDH1A1HSD17B2TSHR | |
| SCHEMBL27455432 | 0.78 | HSD17B2 (0.59) | KMT2AGAAPOLBALDH1A1KDM4E | |
| SCHEMBL20134882 | 0.78 | HSD17B2 (0.68) | KMT2AGAAPOLBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025070947-A1 | NOVEL PHTHALAZINE DERIVATIVE COMPOUND AS SOS1 INHIBITOR, AND USE THEREOF | 한미약품 주식회사 | 2025-04-03 | — | — | WO | disclosed |