SCHEMBL31465622

SCHEMBL31465622

COC(=O)CCCCN1CCNCC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 3/20 0.47
PAOX Q6QHF9 1/20 0.46
HRH2 P25021 1/20 0.45
HRH1 P35367 1/20 0.45
CXCR4 P61073 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GLA P06280 1/20 0.41
CHRM5 P08912 1/20 0.40
CHRM3 P20309 1/20 0.40
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9293161 0.98 PAOX (0.49) MEN1KMT2ATSHRPAOXHRH2
Hydrochloric Acid SCHEMBL9462599 0.97 PAOX (0.47) MEN1KMT2ATSHRPAOXHRH2
Hydrochloric Acid SCHEMBL18263836 0.97 PAOX (0.47) MEN1KMT2ATSHRPAOXHRH2
SCHEMBL7310808 0.95 MEN1 (0.49) MEN1KMT2ATSHRPAOXHRH2
Hydrochloric Acid SCHEMBL28437307 0.93 MEN1 (0.48) MEN1KMT2ATSHRPAOXHRH2
SCHEMBL6603043 0.87 SMN1; SMN2 (0.56) MEN1KMT2ATSHRHRH2HRH1
Hydrochloric Acid SCHEMBL8480707 0.86 SMN1; SMN2 (0.54) MEN1KMT2ATSHRHRH2HRH1
Hydrochloric Acid SCHEMBL4114140 0.86 SMN1; SMN2 (0.54) MEN1KMT2ATSHRHRH2HRH1
SCHEMBL25751543 0.84 TSHR (0.52) KMT2ATSHRPAOXSMN1; SMN2ALDH1A1
SCHEMBL3573381 0.83 HRH2 (0.46) MEN1KMT2ATSHRPAOXHRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049555-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-03-06 WO disclosed