SCHEMBL6603043

SCHEMBL6603043

COC(=O)CCN1CCNCC1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.56
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
TSHR P16473 2/20 0.44
CHRM5 P08912 1/20 0.43
CHRM3 P20309 1/20 0.43
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
HRH2 P25021 1/20 0.39
HRH1 P35367 1/20 0.39
TP53 P04637 1/20 0.39
CACNA1C Q13936 1/20 0.39
HTR4 Q13639 1/20 0.39
POLB P06746 1/20 0.38
PADI1 Q9ULC6 1/20 0.38
PADI4 Q9UM07 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4114140 0.98 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2ATSHRCHRM5
Hydrochloric Acid SCHEMBL8480707 0.98 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2ATSHRCHRM5
SCHEMBL11668777 0.93 SMN1; SMN2 (0.50) SMN1; SMN2MEN1KMT2ATSHRCHRM5
SCHEMBL20561437 0.90 SMN1; SMN2 (0.48) SMN1; SMN2MEN1KMT2ATSHRHSD17B10
SCHEMBL7310808 0.89 MEN1 (0.49) SMN1; SMN2MEN1KMT2ATSHRCHRM5
SCHEMBL16265594 0.89 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2ATSHRCHRM5
Hydrochloric Acid SCHEMBL28437307 0.87 MEN1 (0.48) SMN1; SMN2MEN1KMT2ATSHRCHRM5
SCHEMBL31465622 0.87 MEN1 (0.48) SMN1; SMN2MEN1KMT2ATSHRCHRM5
SCHEMBL9293161 0.86 PAOX (0.49) SMN1; SMN2MEN1KMT2ATSHRALDH1A1
SCHEMBL1174392 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114394898-A Preparation method of 5-oxohexanoate 山东智永化工产业技术研究院有限公司 2022-04-26 CN claimed
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2026-03-26 US disclosed
WO-2024098039-A2 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed
US-20230364251-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES CIDARA THERAPEUTICS, INC. 2023-11-16 US disclosed
US-20230364251-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES CIDARA THERAPEUTICS, INC. 2023-11-16 US disclosed
US-20230364251-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES CIDARA THERAPEUTICS, INC. 2023-11-16 US disclosed
EP-4192512-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES CIDARA THERAPEUTICS, INC. (US) 2023-06-14 EP disclosed
EP-4028392-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2022-07-20 EP disclosed
CN-114728937-A Compositions and methods for treating respiratory syncytial virus 奇达拉治疗公司 2022-07-08 CN disclosed
CN-114394898-A Preparation method of 5-oxohexanoate 山东智永化工产业技术研究院有限公司 2022-04-26 CN disclosed
CN-1052231-C Adhesion receptor antagonists MERCK PATENT GMBH (DE) 2000-05-10 CN disclosed
EP-0623615-B1 Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists MERCK PATENT GMBH (DE) 1999-06-30 EP disclosed
US-5908843-A Piperazine compounds as fibrinogen inhibitors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-06-01 US disclosed
US-5776937-A Adhesion receptor antagonists MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-07-07 US disclosed
EP-0741133-A2 Adhesion receptor antagonists MERCK PATENT GmbH (DE) 1996-11-06 EP disclosed
CN-1132201-A Adhesion receptor antagonists MERCK PATENT GMBH (DE) 1996-10-02 CN disclosed
US-5532255-A Adhesion receptor antagonists MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-02 US disclosed
EP-0711770-A1 Antagonists of adhesion receptors MERCK PATENT GmbH (DE) 1996-05-15 EP disclosed
EP-0623615-A1 Adhesion-receptor antagonists MERCK PATENT GmbH (DE) 1994-11-09 EP disclosed
EP-0608759-A2 Piperazinderivatives MERCK PATENT GmbH (DE) 1994-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS ASGR1, FCGR2A, FCGR3B SMN1; SMN2 4035/4885MEN1 4703/4885KMT2A 4453/4885
US-20230364251-A1 METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES DNPEP, NPEPPS, DHFR SMN1; SMN2 3029/4885MEN1 3895/4885KMT2A 2734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.