Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18263836 | 0.98 | PAOX (0.47) | PAOXCXCR4MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9462599 | 0.98 | PAOX (0.47) | PAOXCXCR4MEN1KMT2ATSHR | |
| SCHEMBL31465622 | 0.98 | MEN1 (0.48) | PAOXCXCR4MEN1KMT2ATSHR | |
| SCHEMBL7310808 | 0.93 | MEN1 (0.49) | PAOXCXCR4MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL28437307 | 0.92 | MEN1 (0.48) | PAOXCXCR4MEN1KMT2ATSHR | |
| SCHEMBL6603043 | 0.86 | SMN1; SMN2 (0.56) | MEN1KMT2ATSHRHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL8480707 | 0.84 | SMN1; SMN2 (0.54) | MEN1KMT2ATSHRHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL4114140 | 0.84 | SMN1; SMN2 (0.54) | MEN1KMT2ATSHRHRH2HRH1 | |
| SCHEMBL28390299 | 0.84 | PAOX (0.53) | PAOXKMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL25540401 | 0.84 | KDM5A (0.45) | PAOXMEN1KMT2ATSHRHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318970-A | Cyclooxygenase, lipoxygenase inhibitors | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0549797-A1 | ISOXAZOLE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MEDICINAL USE THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1993-07-07 | — | — | EP | disclosed |
| US-5182284-A | Antiasthmatic agent, antiallergen, antiinflammatory agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0465659-A1 | PIPERAZINE COMPOUND, PRODUCTION THEREOF, AND MEDICINAL USE THEREOF | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | disclosed |