⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466409 | 0.79 | GPR119 (0.43) | — | |
| SCHEMBL27256143 | 0.65 | HCAR3 (0.39) | — | |
| SCHEMBL15941948 | 0.65 | GAA (0.44) | — | |
| SCHEMBL26271961 | 0.65 | KDM4E (0.42) | — | |
| SCHEMBL23213976 | 0.64 | — | — | |
| SCHEMBL23213685 | 0.64 | KCNH2 (0.37) | — | |
| SCHEMBL23213997 | 0.61 | KMT2A (0.39) | — | |
| SCHEMBL23546415 | 0.60 | GPR119 (0.46) | — | |
| SCHEMBL19300025 | 0.60 | MAPK13 (0.42) | — | |
| SCHEMBL24783613 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |