Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17433761 | 1.00 | NR4A1 (0.52) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| Naphthoic Acid SCHEMBL28057383 | 0.83 | NR4A1 (0.66) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| SCHEMBL1133932 | 0.81 | KDM4E (0.54) | ALDH1A1KDM4ELMNAPOLBMEN1 | |
| SCHEMBL2806839 | 0.81 | MGAM (0.58) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| SCHEMBL8421614 | 0.81 | NPC1 (0.58) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| Potassium SCHEMBL8421620 | 0.81 | NPC1 (0.58) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| SCHEMBL30048398 | 0.79 | ALDH1A1 (0.51) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| SCHEMBL2289118 | 0.79 | ALDH1A1 (0.51) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| SCHEMBL27562798 | 0.79 | NR4A1 (0.50) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 | |
| SCHEMBL12701071 | 0.79 | NR4A1 (0.50) | NR4A1NR4A2NR4A3ALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034128-A1 | BCL-XL INHIBITORS | BEIGENE, LTD. (KY) | 2025-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034128-A1 | BCL-XL INHIBITORS | BCL2, BCL2L1, BCL2L10 | NR4A1 3630/4885NR4A2 2528/4885NR4A3 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.