Sugi Predict

Sugi Predict / Compounds / SCHEMBL2806839

SCHEMBL2806839

SCHEMBL2806839

O=C(O)c1ccc2c(C(=O)O)cccc2n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGAM O43451 1/20 0.58
▸ ALOX15 P16050 4/20 0.54
▸ KDM4E B2RXH2 3/20 0.54
▸ TSHR P16473 1/20 0.54
▸ ACMSD Q8TDX5 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ NR4A1 P22736 1/20 0.52
▸ NR4A2 P43354 1/20 0.52
▸ NR4A3 Q92570 1/20 0.52
▸ ALDH1A1 P00352 4/20 0.50
▸ PTPN1 P18031 1/20 0.49
▸ HPGD P15428 2/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ KMT2A Q03164 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ NPC1 O15118 2/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ TP53 P04637 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29098349 0.83 MGAM (0.45) MGAMALOX15KDM4ENR4A1NR4A2
SCHEMBL5181112 0.81 MGAM (0.58) MGAMALOX15KDM4ETSHRACMSD
Potassium SCHEMBL8421620 0.81 NPC1 (0.58) KDM4ETDP1NR4A1NR4A2NR4A3
SCHEMBL31466752 0.81 NR4A1 (0.52) ALOX15KDM4ENR4A1NR4A2NR4A3
SCHEMBL17433761 0.81 NR4A1 (0.52) ALOX15KDM4ENR4A1NR4A2NR4A3
SCHEMBL8421614 0.81 NPC1 (0.58) KDM4ETDP1NR4A1NR4A2NR4A3
SCHEMBL18365930 0.79 MGAM (0.56) MGAMALOX15KDM4ETSHRACMSD
SCHEMBL2909537 0.79 MGAM (0.56) MGAMALOX15KDM4ETSHRACMSD
SCHEMBL6193849 0.79 MGAM (0.56) MGAMALOX15KDM4ETSHRACMSD
SCHEMBL2289118 0.79 ALDH1A1 (0.51) KDM4ENR4A1NR4A2NR4A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478970-A Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2022-05-13 — — CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US claimed
CN-114478970-B Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2023-11-03 — — CN disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 — — EP disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 — — US disclosed
CN-114478970-A Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2022-05-13 — — CN disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 — — WO disclosed
CN-112978709-A Carbon quantum dot precursor composition, carbon quantum dot and preparation method thereof 中国科学院大连化学物理研究所 2021-06-18 — — CN disclosed
CN-105755480-A Efficient acidic cleaner 江苏筑磊电子科技有限公司 2016-07-13 — — CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 — — US disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 MGAM 1091/4885ALOX15 914/4885KDM4E 2504/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB MGAM 2758/4885ALOX15 608/4885KDM4E 1615/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA MGAM 2257/4885ALOX15 383/4885KDM4E 1109/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA MGAM 3909/4885ALOX15 1704/4885KDM4E 2585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.