Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984705 | 1.00 | CYP1A2 (0.53) | CYP1A2SMN1; SMN2CYP2C9CYP2C19GCK | |
| SCHEMBL22309177 | 0.81 | LMNA (0.49) | CYP1A2GCK | |
| SCHEMBL30457774 | 0.81 | LMNA (0.49) | CYP1A2GCK | |
| SCHEMBL17161028 | 0.81 | MAPT (0.42) | CYP1A2KDM4EHSD17B10KMT2ARAB9A | |
| SCHEMBL22116755 | 0.77 | GRM5 (0.42) | CYP1A2KDM4EHSD17B10KMT2ATDP1 | |
| SCHEMBL11170285 | 0.77 | TDP1 (0.60) | CYP1A2SMN1; SMN2CYP2C9CYP2C19GCK | |
| SCHEMBL26984691 | 0.75 | TDP1 (0.51) | CYP1A2SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL31466991 | 0.75 | TDP1 (0.51) | CYP1A2SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL21591101 | 0.74 | L3MBTL1 (0.38) | CYP1A2KDM4EHSD17B10RAB9ANPC1 | |
| SCHEMBL16926500 | 0.74 | GCK (0.53) | CYP1A2CYP2C9CYP2C19GCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677716-A | Pharmaceutical compositions comprising WRN helicase inhibitors | 维维迪恩医疗公司 | 2025-03-21 | — | — | CN | disclosed |