Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20957055 | 0.84 | MAPT (0.50) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL31467503 | 0.84 | MAPT (0.72) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20957019 | 0.83 | MAPT (0.48) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL31467485 | 0.83 | MAPT (0.48) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20988353 | 0.82 | MAPT (0.47) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20956994 | 0.82 | MAPT (0.48) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20957054 | 0.82 | MAPT (0.47) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20956983 | 0.80 | MAPT (0.67) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20956995 | 0.80 | GAA (0.46) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20988440 | 0.80 | GFER (0.47) | MAPTGAATP53GFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049643-A1 | NOX4 INHIBITORS AND METHODS OF MAKING AND USING SAME | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2025-03-06 | — | — | WO | disclosed |