SCHEMBL31468641

SCHEMBL31468641

COC(OC)[SiH2]CCCN1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
KEAP1 Q14145 1/20 0.44
ALDH1A1 P00352 6/20 0.41
MAPK1 P28482 2/20 0.41
SIGMAR1 Q99720 2/20 0.41
CYP1A2 P05177 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
HTR2A P28223 1/20 0.41
SCN1A P35498 1/20 0.41
HTR2B P41595 1/20 0.41
KCNH2 Q12809 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
TSHR P16473 3/20 0.40
CYP2D6 P10635 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11897268 0.87 MAOB (0.32) SMN1; SMN2KCNH2HRH3
SCHEMBL1995695 0.84 HRH3 (0.41) SMN1; SMN2ALDH1A1MAPK1CYP1A2KCNH2
SCHEMBL31468523 0.83 ALDH1A1 (0.42) SMN1; SMN2KEAP1ALDH1A1MAPK1SIGMAR1
SCHEMBL12002828 0.82 PAOX (0.37) ALDH1A1SIGMAR1HRH3USP2HPGD
SCHEMBL4827221 0.82 HRH3 (0.45) SMN1; SMN2ALDH1A1MAPK1CYP1A2KCNH2
SCHEMBL22206788 0.80
SCHEMBL1995367 0.80 CSNK2A2 (0.30)
SCHEMBL1229306 0.79 CXCR4 (0.42) SMN1; SMN2SIGMAR1CHRM2CHRM1HRH3
SCHEMBL2413049 0.78 USP2 (0.38) SMN1; SMN2KEAP1ALDH1A1TSHRCYP2D6
SCHEMBL1230442 0.74 HRH3 (0.38) HRH3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 SMN1; SMN2 1908/4885KEAP1 2412/4885ALDH1A1 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.