Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421959 | 1.00 | MKNK1 (0.52) | MKNK1MKNK2TDO2VHLTDP1 | |
| SCHEMBL9963986 | 0.88 | NOS3 (0.46) | MKNK1MKNK2TDO2VHLTDP1 | |
| SCHEMBL27941864 | 0.87 | MKNK1 (0.56) | MKNK1MKNK2TDO2VHLTDP1 | |
| SCHEMBL23731203 | 0.86 | NOS3 (0.56) | MKNK1MKNK2TDO2VHLNOS3 | |
| SCHEMBL28231982 | 0.86 | KDM4E (0.50) | MKNK1MKNK2TDO2VHLGAA | |
| SCHEMBL15730138 | 0.84 | MKNK1 (0.50) | MKNK1MKNK2TDO2VHLHTT | |
| SCHEMBL18174898 | 0.84 | VHL (0.43) | MKNK1MKNK2TDO2VHLPDE2A | |
| SCHEMBL15731251 | 0.84 | PDE2A (0.48) | MKNK1MKNK2TDO2VHLKMT2A | |
| SCHEMBL4446669 | 0.84 | MKNK1 (0.46) | MKNK1MKNK2TDO2VHLMEN1 | |
| SCHEMBL30563610 | 0.83 | MKNK1 (0.58) | MKNK1MKNK2TDO2VHLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025029860-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | ADCENTRX THERAPEUTICS INC. (US) | 2025-02-06 | — | — | WO | disclosed |