Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421959 | 0.84 | MKNK1 (0.52) | VHLMKNK1MKNK2TDO2PTPRC | |
| SCHEMBL31469002 | 0.84 | MKNK1 (0.52) | VHLMKNK1MKNK2TDO2PTPRC | |
| SCHEMBL2213332 | 0.80 | — | — | |
| SCHEMBL9963986 | 0.78 | NOS3 (0.46) | VHLMKNK1MKNK2TDO2ELANE | |
| SCHEMBL17117972 | 0.78 | ALDH1A1 (0.44) | PSMD14COPS5PTPRCCTSLCTSS | |
| SCHEMBL28231982 | 0.77 | KDM4E (0.50) | VHLMKNK1MKNK2TDO2PDE2A | |
| SCHEMBL18174897 | 0.76 | CYP2A6 (0.46) | PSMD14COPS5PTPRCCTSLCTSS | |
| SCHEMBL4446669 | 0.75 | MKNK1 (0.46) | VHLMKNK1MKNK2TDO2IDO1 | |
| SCHEMBL15730138 | 0.75 | MKNK1 (0.50) | VHLMKNK1MKNK2TDO2PTPRC | |
| SCHEMBL15731251 | 0.75 | PDE2A (0.48) | VHLMKNK1MKNK2TDO2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9478758-B1 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-10-25 | — | — | US | disclosed |