Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184060 | 0.90 | ALDH1A1 (0.47) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL16981203 | 0.85 | ALDH1A1 (0.50) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL13024337 | 0.82 | L3MBTL1 (0.45) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL3464755 | 0.80 | HTR2A (0.41) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL8265598 | 0.78 | HPGD (0.50) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL23579385 | 0.78 | ALDH1A1 (0.41) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL3201532 | 0.76 | KDM4E (0.55) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL10775946 | 0.76 | L3MBTL1 (0.67) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL10775846 | 0.76 | L3MBTL1 (0.67) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL3464649 | 0.76 | HPGD (0.51) | KDM4EMAPTPOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684313-A | Macrocyclic compound and preparation method and application thereof | 上海爱科百发生物医药技术股份有限公司 | 2025-03-25 | — | — | CN | disclosed |