Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27902631 | 0.98 | LMNA (0.63) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| SCHEMBL81625 | 0.98 | LMNA (0.63) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| SCHEMBL30779764 | 0.96 | LMNA (0.61) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| Hydrochloric Acid SCHEMBL7143179 | 0.96 | L3MBTL1 (0.61) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| Iodide SCHEMBL1841532 | 0.96 | LMNA (0.61) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| Water SCHEMBL10592152 | 0.96 | LMNA (0.61) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| Iodomethane SCHEMBL11514034 | 0.95 | LMNA (0.59) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| Pentane SCHEMBL19922721 | 0.90 | POLB (0.57) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 | |
| SCHEMBL31270697 | 0.88 | LMNA (0.74) | LMNAL3MBTL1HSD17B10ALDH1A1KMT2A | |
| SCHEMBL11420217 | 0.87 | LMNA (0.52) | LMNAL3MBTL1HSD17B10ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119701994-A | Ferromanganese-based catalyst for preparing methyl methacrylate and preparation and application thereof | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |