Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 7/20 | 0.40 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021772 | 0.84 | HTT (0.57) | HTTLMNASMN1; SMN2ALDH1A1CCNC | |
| SCHEMBL4548650 | 0.79 | CHEK1 (0.47) | HTTLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL31236169 | 0.76 | PDE4A (0.53) | HTTLMNASMN1; SMN2ALDH1A1CCNC | |
| SCHEMBL858150 | 0.76 | PDE4A (0.53) | HTTLMNASMN1; SMN2ALDH1A1CCNC | |
| SCHEMBL13783329 | 0.76 | RXFP1 (0.49) | MPOHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12143429 | 0.76 | MPO (0.45) | MPOHTTEGFRKDRCDK1 | |
| SCHEMBL16755291 | 0.76 | PI4KA (0.53) | HTTLMNASMN1; SMN2EGFRFBP1 | |
| SCHEMBL19044344 | 0.76 | EGFR (0.39) | EGFRFBP1GAKERBB2 | |
| SCHEMBL1947700 | 0.76 | LMNA (0.46) | HTTLMNASMN1; SMN2ALDH1A1CCNC | |
| SCHEMBL16755307 | 0.76 | EGFR (0.57) | HTTLMNASMN1; SMN2CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |