Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110568 | 0.86 | ALK (0.41) | ALKDYRK1AGSK3BWNT1MCL1 | |
| SCHEMBL38651284 | 0.83 | MCL1 (0.40) | DYRK1AGSK3BWNT1MCL1AXL | |
| SCHEMBL31469324 | 0.80 | ATR (0.40) | MCL1 | |
| SCHEMBL31469312 | 0.78 | ALK (0.44) | ALKDYRK1AGSK3BWNT1EGFR | |
| SCHEMBL26112400 | 0.77 | ALK (0.45) | ALKDYRK1AGSK3BWNT1RIPK1 | |
| SCHEMBL26111614 | 0.77 | ALK (0.47) | ALKDYRK1AGSK3BRIPK1EGFR | |
| SCHEMBL26110531 | 0.75 | AURKB (0.42) | ALKMCL1AXL | |
| SCHEMBL26114155 | 0.75 | AURKB (0.40) | ALKMCL1AXL | |
| SCHEMBL31469256 | 0.72 | ALDH1A1 (0.44) | GSK3BEGFR | |
| SCHEMBL26112104 | 0.72 | DYRK1A (0.46) | ALKDYRK1AGSK3BWNT1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |